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Exenatide acetate is , while it's Molecular Formula is C184H282N50O60S.C2H4O2. Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.
The CAS number of Exenatide acetate is 141732-76-5.
More information of Exenatide acetate 141732-76-5 are:
|
Synonyms |
Exendin4;UNII-9P1872D4OL;Extendin-4; |
|
CAS Number |
141732-76-5 |
|
Molecular Formula |
C184H282N50O60S.C2H4O2 |
|
Molecular Weight |
4262.67 |
|
PSA |
1812.35000 |
|
LogP |
-2.07850 |
Exenatide acetate is a 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum). It differs from exendin-3 only in two positions close to the N-terminus and is a white solid. As an incretin mimetic, exenatide acetate acts as an agonist of the glucagon-like peptide-1 (GLP-1) receptor, similar to GLP-1 but with prolonged activity. It increases the postprandial production of insulin and suppresses the secretion of glucagon.
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