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Substance P is white powder, while it's Molecular Formula is C63H98N18O13S. Used in Pharmaceutical Industry:
Substance P is used as a target for the development of drugs aimed at treating pain and inflammation. Its involvement in the transmission of pain signals and inflammatory responses makes it a significant therapeutic target for analgesics and anti-inflammatory medications.
Used in Research and Development:
Substance P serves as a subject of interest in research and development, particularly in the fields of neuroscience, neurobiology, and pharmacology. Understanding its role in pain transmission and inflammation can lead to the discovery of new treatments for various conditions related to these processes.
Used in Diagnostics:
Substance P can be used as a biomarker in diagnostics to identify and monitor inflammatory conditions and pain-related disorders. Its presence and levels in the body can provide valuable information about the severity and progression of certain diseases.
The CAS number of Substance P is 33507-63-0.
More information of Substance P 33507-63-0 are:
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Synonyms |
1: PN:US20020037833 SEQID: 1 unclaimed sequence;21: PN: WO0181408 SEQID: 44 claimedprotein;2: PN: JP2005049164 SEQID: 2 claimed protein;36: PN: WO2007058336SEQID: 36 claimed protein;44: PN: WO2005016244 PAGE: 68 claimed protein;690:PN: WO2004005342 PAGE: 46 claimed protein;L-Methioninamide,L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-;Neurokinin P;Substance P (1-11);Substance P (peptide);Substance P(smooth-muscle stimulant);N5-(diaminomethylidene)-L-ornithyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide; |
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CAS Number |
33507-63-0 |
|
Molecular Formula |
C63H98N18O13S |
|
Molecular Weight |
1347.65 |
|
Density |
1.42 g/cm3 |
|
Melting Point |
148 °C |
|
PSA |
544.43000 |
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LogP |
4.19410 |
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Pka |
13.26±0.46(Predicted) |
Substance P is a polypeptide consisting of 11 amino acid residues, playing a crucial role in the transmission of "painful" sensory information through the spinal cord to higher centers in the central nervous system. It is localized in the primary afferent sensory fibers and is involved in various pharmacological effects, including vasodilation, stimulation of smooth muscles, stimulation of salivary secretion, and diuresis. Additionally, this neuropeptide contributes to some inflammatory responses.
InChI:InChI=1/C63H98N18O13S/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(88)42(23-25-50(66)82)75-55(87)43(24-26-51(67)83)76-59(91)49-22-14-31-81(49)62(94)44(20-10-11-28-64)77-60(92)48-21-13-30-80(48)61(93)40(65)19-12-29-71-63(69)70/h4-9,15-18,37,40-49H,10-14,19-36,64-65H2,1-3H3,(H2,66,82)(H2,67,83)(H2,68,85)(H,72,86)(H,73,84)(H,74,89)(H,75,87)(H,76,91)(H,77,92)(H,78,90)(H,79,88)(H4,69,70,71)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-/m0/s1
Articles related to Substance P:
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Article |
Source |
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Tachykinin NK-1 receptor probed with constrained analogues of substance P |
Sagan, Sandrine,Josien, Hubert,Karoyan, Philippe,Brunissen, Alie,Chassaing, Gerard,Lavielle, Solange , p. 2167 - 2178 (2007/10/03) |
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Catalytic Transfer Hydrogenation in Synthesis of Substance P |
Sivanandaiah, K. M.,Rangaraju, N. S. , p. 787 - 792 (2007/10/02) |
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