Glucagon

Quality products make an important contribution to long-term revenue and profitability. Cost-effective and customizable Glucagon 16941-32-5 supplier

1.What is the Glucagon ?

Oral administration of this product is invalid, injection treatment is frequently applied. The action time in vivo is short; it will work after? 5 minutes of intravenous injection. Blood glucose can be increased by 50% in 30 minutes. It is sustainable about 1 hour. It mainly inactivated in the liver, kidney and plasma. Plasma half-life time is 3 to 6 minutes. In clinical practice, it is used for insulin-dependent diabetes patients with severe hypoglycemic coma and the disability to eat, but also for the determination of pancreatic function, diagnosis of pancreatic tumor and pheochromocytoma. It is mainly used for acute heart failure, digitalis ineffective heart failure, heart failure with cardiogenic shock for circulatory system use. The efficacy of glucagon on chronic heart failure is poor. The main indications are as follows: ① acute low-emission syndrome. ② coronary heart disease and cardiomyopathy caused by acute heart failure or cardiogenic shock. ③ arrhythmia caused by the combined treatment of propranolol to digitalis poisoning.

Glucagon is a polypeptide secreted by the α cells of the pancreatic islets. Its physiological actions include stimulation of hepatic gluconeogenesis in response to hypoglycaemia and amino acids and as part of the stress response. These effects are mediated by increasing adenylate cyclase activity and intracellular cAMP by a mechanism independent of the β-adrenergic receptor. It increases cAMP in myocardial cells and so increases cardiac contractility. Glucagon causes nausea and vomiting, hyperglycaemia and hyperkalaemia and is not used as an inotrope except in the management of β-blocker poisoning.

2.What is the CAS number for Glucagon ?

The CAS number of Glucagon is 16941-32-5.

More information of Glucagon 16941-32-5 are:

3.What are another words for Glucagon ?

Synonyms for Glucagon 16941-32-5:Glucagon

4.What is the molecular formula of Glucagon?

The chemical formula of  Glucagon is C153H225N43O49S which containing 153 Carbon atoms,225 Hydrogen atoms,43 Nitrogen atoms,49 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of  Glucagon is 3482.75.

5.What is Glucagon (16941-32-5) used for?

Glucagon is a hyperglycemic-glycogenolytic hormone produced by the α-cells of the pancreatic islets and also by the gastric mucosa. It is a straight-chain polypeptide containing 29 amino acid residues with a molecular weight of approximately 3500. Glucagon has opposite effects to insulin and plays a crucial role in regulating blood glucose levels. It is a white or almost white powder, soluble in specific pH ranges, and stable under certain conditions.

InChI:InChI=1/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3

Relevant articles related to Glucagon:

6.Buy Glucagon with the best price .

Xi'an Youbo Hui Biotechnology Co., Ltd. is a quality supplier of Glucagon. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Glucagon 16941-32-5.