Argipressin

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1.What is the Argipressine ?

ADH (vasopressin) is released primarily in response to increases in plasma osmolarity or decreases in blood volume. It produces its antidiuretic activity in the kidney, causing the cortical and medullary parts of the collecting duct to become more permeable to water, thereby increasing water reabsorption, reducing serum osmolarity, and increasing its volume. It produces this effect by binding to a subset of vasopressin receptors called V2 that have relatively high affinity for the hormone. ADH also has actions at sites other than the kidney. V2 receptors also mediate an increase in circulating levels of two proteins involved in blood coagulation: factor VIII and von Willebrand’s factor.At higher concentrations, ADH interacts with V1 receptors to cause a general constriction of most blood vessels. It also interacts with V3 (or V1b) receptors to increase ACTH release, although the major control of ACTH release occurs through corticotropin-releasing hormone.

[Arg8]-Vasopressin solution was used as an antigen for preparing preadsorbed antisera for immunocytochemistry. The product was used in L6 cell culture of the C5 subclone for differentiation studies.

2.What is the CAS number for Argipressine ?

The CAS number of Argipressine is 113-79-1.

More information of Argipressine 113-79-1 are:

3.What are another words for Argipressine ?

Synonyms for Argipressine 113-79-1:3-(Phenylalanine)-8-arginineoxytocin;8-L-Arginine-vasopressin;AVP;Arg8-vasopressin;Arginine antidiuretic hormone;Arginine-8-vasopressin;Arginine-vasopressin;1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide,19-amino-13-benzyl-7-(carbamoylmethyl)-4-[2-[[1-[(carbamoylmethyl)carbamoyl]-4-guanidinobutyl]carbamoyl]-1-pyrrolidinylcarbonyl]-16-p-hydroxybenzyl-6,9,12,15,18-pentaoxo-(6CI);

4.What is the molecular formula of Argipressine?

The chemical formula of  Argipressine is C46H65N15O12S2 which containing 46 Carbon atoms,65 Hydrogen atoms,15 Nitrogen atoms,12 Oxygen atoms and 2 Sulfur atoms,and the molecular weight of  Argipressine is 1084.25.

5.What is Argipressine (113-79-1) used for?

Argipressine, also known as [Arg8]-Vasopressin, is the predominant form of mammalian vasopressin, an antidiuretic hormone. It is a nonapeptide containing an arginine at residue 8 and two disulfide-linked cysteines at residues 1 and 6. Argipressine is available under the brand name Pitressin (Parke-Davis).

InChI:InChI=1/C46H65N15O12S2.C2H4O2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25;1-2(3)4/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53);1H3,(H,3,4)/t27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1

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