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Leuprorelin is Fluffy solid., while it's Molecular Formula is C59H84N16O12. Gonadotropin releasing hormone (gonadorelin) analogue; treatment of prostate cancer.
The CAS number of Leuprorelin is 53714-56-0.
More information of Leuprorelin 53714-56-0 are:
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Synonyms |
Luteinizinghormone-releasing factor (pig),6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-;(D-Leu6,des-Gly-NH210)-LH-RH ethylamide;D-Leu6-des-Gly10-LH-releasing hormone ethylamide;Des-Gly10-[D-Leu6]-LH-releasing hormone ethylamide;Des-Gly10-[D-Leu6]LH-RHethylamide;1-9-Luteinizinghormone-releasing factor (swine), 6-D-leucine-9-(N-ethyl-L-prolinamide)-;Leuprorelin;Lupron SR;NSC 377526; |
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CAS Number |
53714-56-0 |
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Molecular Formula |
C59H84N16O12 |
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Molecular Weight |
1209.42 |
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Density |
1.44 g/cm3 |
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PSA |
466.34000 |
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LogP |
3.44730 |
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Pka |
9.82±0.15(Predicted) |
Leuprorelin(Leuprolide?) is a synthetic water-soluble nonapeptide with both ends closed, and also a highly active analogue of luteinizing hormone releasing hormone (LHRH or GnRH) produced by the hypothalamus. It can stimulate the pituitary gland to secrete gonadotropins and induce the production of steroids in the reproductive organs.
InChI:InChI=1/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1
Articles related to Leuprorelin:
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Article |
Source |
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Synthesis, Stability and Direct Antiproliferative Effect of New Cysteine Modified GnRH Analogs |
Li, Songtao,Zhao, Hongling,Wang, Ruxing,Wang, Jianping,Mao, Xiaoxia,Hao, Ting,Chang, Xiaomin,Zhao, Enhong,Yin, Zhifeng,Deng, Shuhua,Yang, Yaqi,Wang, Huina , p. 1361 - 1367 (2019) |
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A catalytic one-step synthesis of peptide thioacids: the synthesis of leuprorelin via iterative peptide-fragment coupling reactions |
Matsumoto, Takuya,Sasamoto, Koki,Hirano, Ryo,Oisaki, Kounosuke,Kanai, Motomu supporting information, p. 12222 - 12225 (2018/12/01) |
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